The FDA granted accelerated approval to Voceryq, a plasmid DNA-based immunotherapy for adults with recurrent respiratory papillomatosis.
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Another Win For Novel Drug, This Time In EGFR-Mutated Lung Cancer
In a 432-patient phase III China trial, izalontamab brengitecan improved median PFS over chemotherapy, with more severe treatment-related side effects.
Trio Of IgA Nephropathy Drugs Proves Mettle In Interim Analyses
Interim phase III analyses found lower proteinuria with povetacicept, ravulizumab and sefaxersen; longer-term kidney-function data are still pending.
Scientists Identify Novel Autoimmune Driver Behind DNA Repair Breakdown In Childhood Cancer
A Norwegian study links antibodies targeting DNA repair proteins with childhood cancer and reports they were present in some children years before diagnosis.
Bowel Cancer “Melted Away” After Immunotherapy, Then Stayed Away
A 32-patient UK trial reported no bowel cancer recurrences after almost three years following pembrolizumab before surgery.
New Oral Drug Approved For Herpes Lesions
The FDA approved once-daily pritelivir for HSV lesions in immunocompromised patients whose infections have not responded to other treatments.
Researchers Identify New Protein Regulator Of Muscle Stem Cell Differentiation
A study in eLife links the protein LMOD1 to early muscle stem cell differentiation and interaction with SIRT1 in mouse cells and injured muscle.
LVADs Linked To Concerning Neurologic Events, Strokes Aside
A U.S. registry study found nonstroke neurologic events were as common as strokes after HeartMate 3 implantation and were associated with lower survival.
Lessons From A Year Of RFK Jr. Disinformation
A MedPage Today opinion article reviews a year of tracking Robert F. Kennedy Jr.’s health claims and argues they undermine trust in public health.
Sex Chromosomes Influence Immunity, Cancer, Aging And Disease Risk
A Science review synthesizes evidence that sex chromosomes influence immunity, cancer, aging and other diseases, alongside hormones.